About me

Dr. rer. nat. Felix Bormann
I am a biologist by training who discovered the joy of bioinformatics.
Now I want to help other scientists to increase their impact by including high throughput data into their research.

Computer Skills:

R statistics, Python, Perl, PHP, HTML, JavaScript, CWL, Docker-based applications. specialized in High-throughput analysis and analysis of large datasets

Quick learning skills for other computer languages

Work Experience:

01.12.2014 – 31.10.2018German Cancer Research Center (DKFZ), Heidelberg, Germany; Division of Epigenetics (Prof. Dr. Frank Lyko): Postdoc
15.05.2007 – 31.03.2009Max Planck Institute for Molecular Genetics, Berlin, Germany; Miniaturization for Functional Genetics (Dr. A. Dahl): Student research assistant

Education:

01.05.2009 – 24.04.2014Humboldt University of Berlin, Berlin, Germany; Conferral of doctorate in molecular biology;
Doctor’s thesis at: Charité Berlin, Institute for Pathology, Molecular Tumor Pathology (Prof. Dr. C. Sers): Title: “The Epigenetic Regulation of the EGF-receptor Ligands Amphiregulin and Epiregulin and Its Impact on the Outcome of EGFR-targeted Therapies.”
01.04.2004 – 31.03.2009Free University of Berlin, Berlin, Germany; Diploma in biochemistry;
Diploma thesis at: Max Planck Institute for Molecular Genetics, Miniaturization for Functional Genetics (Dr. A. Dahl): Title: “Development of a Multiplex Assay for Robust Determination of Epigenetic Changes in Genomic Regions, Associated with the Formation of Colorectal Cancer.”

Publications:

First author publications:

Bormann F, Sers C, Seliger B, et al., Methylation-specific ligation detection reaction (msLDR): a new approach for multiplex evaluation of methylation patterns., Mol Genet Genomics. 2011 Oct;286(3-4):279-91.

Bormann F, Dahl A, Sers C, MsLDR-creator: a web service to design msLDR assays., Mol Genet Genomics. 2012 Mar;287(3):273-4.

Bormann F, Rodríguez-Paredes M, Hagemann S, et al., Reduced DNA methylation patterning and transcriptional connectivity define human skin aging., Aging Cell. 2016 Jun;15(3):563-71

Bormann F, Stinzing S, Tierling S, et al., Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer., Int J Cancer. 2018 Sep 25. doi: 10.1002/ijc.31892

Bormann F, Rodríguez-Paredes M, Lasitschka F et al., Cell-of-Origin DNA Methylation Signatures Are Maintained during Colorectal Carcinogenesis., Cell Rep. 2018 Jun 12;23(11):3407-3418. doi: 10.1016/j.celrep.2018.05.045

Bormann F, Tuorto F, Cirzi C et al., BisAMP: A web-based pipeline for targeted RNA cytosine-5 methylation analysis., Methods 2018 Oct 24. pii: S1046-2023(18)30186-5. doi: 10.1016/j.ymeth.2018.10.013. [Epub ahead of print]

Other publications:

Linhart H, Bormann F, Hutter B, et al. Genetic and
epigenetic profiling of a solitary Peutz-Jeghers colon polyp.
Cold Spring Harb Mol Case Stud. 2017 May;3(3):a001610

Rodríguez-Paredes M, Bormann F, Raddatz G et al. Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cell types of origin. Nat Commun. 2018 Feb 8;9(1):577.